The URI Commands plugin enables users to add custom URI-based commands to the Obsidian command palette, enhancing integration with Obsidian's URI scheme and other system-supported URI schemes. It allows for dynamic placeholders such as file name, path, content, and metadata, which are automatically URL-encoded for seamless use. This flexibility supports a wide range of use cases, from opening vaults or specific notes in Obsidian to integrating with external programs and services like email, Spotify, or HackMD. Users can customize URIs to perform tasks like appending text to a daily note, opening external websites, or interacting with metadata fields. The plugin is compatible with other tools like Advanced URI and Hotkey Helper for extended functionality.